The provisional matrix is the term given to the temporary extracellular matrix that cells assemble during wound healing. Evidence indicates that in the setting of many diseases, including fibrotic diseases and cancer, cells assemble a similar matrix. This matrix is primarily composed of a protein known as fibronectin, which has unique mechanical properties that alter cellular response. We experimentally investigate the effects of fibronectin fibrils on cellular mechanical responses, and, in conjunction with Dr. Seth Weinberg's lab, build computational models of fibronectin fibrils to better understand the relationship between form and function in these important provisional matrix fibrils.